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Hoth Therapeutics Announces CRADA With U.S. Department Of Veterans Affairs And FAVER To Evaluate GDNF As Metabolic Therapy Targeting Obesity And Hepatic Steatosis

Author: Benzinga Newsdesk | July 22, 2025 07:20am

Hoth Therapeutics, Inc. (NASDAQ:HOTH), a clinical-stage biopharma innovator, today announced a CRADA (Cooperative Research and Development Agreement) with the U.S. Department of Veterans Affairs and Foundation for Atlanta Veterans Education and Research (FAVER) to evaluate GDNF (glial cell-derived neurotrophic factor) as a novel metabolic therapy targeting obesity and hepatic steatosis (fatty liver disease).

The study, conducted at the Atlanta VA Medical Center, will benchmark daily GDNF injections against semaglutide in both standard diet-induced obese mice and human liver chimeric mouse models, a gold-standard translational platform.

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