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Inspire Medical Systems, Ichor Holdings, Vertex Pharmaceuticals And Other Big Stocks Moving Lower In Tuesday's Pre-Market Session

Author: Avi Kapoor | August 05, 2025 07:09am

U.S. stock futures were higher this morning, with the Dow futures gaining around 0.1% on Tuesday.

Shares of Inspire Medical Systems, Inc. (NYSE:INSP) fell sharply in pre-market trading after the company reported second-quarter results and cut its FY25 guidance below estimates.

Inspire Medical Systems shares tumbled 25% to $98.00 in the pre-market trading session.

Here are some other stocks moving lower in pre-market trading.

  • Ichor Holdings, Ltd. (NASDAQ:ICHR) declined 24.3% to $15.24 in pre-market trading after the company reported worse-than-expected second-quarter adjusted EPS results and issued third-quarter adjusted EPS guidance below estimates.
  • Gartner, Inc. (NYSE:IT) fell 15% to $287.20 in pre-market trading after the company issued soft FY25 guidance.
  • Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) declined 14.5% to $403.85 in pre-market trading following the release of its second-quarter financial results. Additionally, the company announced results from its Vx-993 Phase 2 trial.
  • Semrush Holdings, Inc. (NYSE:SEMR) fell 14.1% to $7.91 in pre-market trading after the company reported a second-quarter EPS miss.
  • Navitas Semiconductor Corporation (NASDAQ:NVTS) shares fell 14.1% to $6.92 in pre-market trading after the company issued third-quarter sales guidance below estimates..
  • Kyndryl Holdings, Inc. (NYSE:KD) fell 12.2% to $32.21 in pre-market trading after the company reported a first-quarter revenue miss.

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Posted In: ICHR INSP IT KD NVTS SEMR VRTX

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