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Nuwellis Announces First Patients Have Been Successfully Treated With Aquadex Ultrafiltration Therapy In A Hospital-Based Outpatient Setting.

Author: Benzinga Newsdesk | August 05, 2025 07:17am

 Nuwellis, Inc. (NASDAQ:NUWE), a medical technology company dedicated to transforming fluid management, today announced that the first patients have been successfully treated with Aquadex® ultrafiltration therapy in a hospital-based outpatient setting. This milestone reflects a major advancement in the company's mission to improve access to fluid management and support better care across the continuum.

The treatments were performed at a leading healthcare institution in the southeastern United States using the same Aquadex SmartFlow® system and clinical protocols trusted in inpatient environments. By enabling therapy in a hospital-based outpatient setting, Nuwellis is helping to reimagine how and where patients with fluid overload can be supported—offering a potential new model for earlier, more proactive care.

"For patients struggling with fluid overload, access to consistent, effective therapy can make a life-changing difference," said John Erb, CEO of Nuwellis. "This milestone represents more than just a shift in setting—it reflects our vision for expanding how care is delivered and making fluid management more flexible, scalable, and patient-centered."

In addition to the clinical benefits, hospitals may also realize significant economic advantages by transitioning appropriate therapies to outpatient care. With outpatient reimbursement increasing from approximately $413 to $1,639 per treatment day, this model offers a more sustainable path forward for health systems facing pressure to reduce readmissions while managing complex patients more effectively.

The hospital-based outpatient setting provides an opportunity to treat patients using existing venous access and care teams, without requiring hospitalization. This approach may offer significant advantages to patients who are repeatedly admitted due to volume challenges, while also helping healthcare systems manage resources more efficiently.

Posted In: NUWE

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