NeOnc Technologies Awarded $2.5M In NIH Grants To Advance CNS Cancer Drug NEO212 Toward Phase 2

Author: Benzinga Newsdesk | August 07, 2025 08:06am

NeOnc Technologies Holdings, Inc. (NASDAQ:NTHI), a multi–Phase 2 clinical-stage biotechnology company focused on breakthrough therapies for central nervous system (CNS) malignancies, today announced the award of two competitive NIH STTR (Small Business Technology Transfer) grants totaling $2.5 million. These non-dilutive funds will further advance development of the company's proprietary therapeutic compound NEO212, which is currently completing its Phase 1 clinical trial.

• $400,000 Phase 1 STTR Grant (1R41CA27179-01A1): Supports preclinical feasibility studies of NEO212 in acute myelogenous leukemia (AML). Dr. Thomas Chen serves as NeOnc's Principal Investigator (PI), with Dr. Axel H. Schönthal leading the academic research effort at USC's Glioma Research Group.
• $2.1 Million Phase 2 STTR Grant (2R42CA246902-02): Focused on expanding NEO212's clinical development into newly diagnosed gliomas, reinforcing the therapeutic's broad oncologic potential. Dr. Chen is the PI for NeOnc, with Dr. Radu Minea leading the USC component.

These prestigious NIH awards arrive as NeOnc approaches the end-of-Phase 1 milestone for NEO212, marking a pivotal point in the company's path toward Phase 2 trial initiation and potential regulatory engagement.

Posted In: NTHI