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Acadia Pharma Announces Publication Of Interim Results From LOTUS Study On DAYBUE For Rett Syndrome In Developmental Medicine And Child Neurology Journal

Author: Benzinga Newsdesk | September 12, 2025 03:07pm

-- Findings reinforce efficacy and tolerability profile in patients prescribed DAYBUE in the U.S. for as long as 12 months, consistent with the Phase 3 LAVENDER™ trial that supported FDA approval and open-label LILAC, LILAC-2 and DAFFODIL studies

Acadia Pharmaceuticals Inc. (NASDAQ:ACAD) today announced that the journal Developmental Medicine and Child Neurology published interim results from the caregiver-reported observational online, open-label, ongoing LOTUS study evaluatingeffectiveness and tolerability outcomes in patients with Rett syndrome who are prescribed DAYBUE® (trofinetide)under routine clinical care in the U.S. Findings included reported improvements in symptoms of Rett syndrome, with early insights into managing gastrointestinal (GI) symptoms in the real world among patients receiving up to 12 months of treatment with DAYBUE.

Posted In: ACAD

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