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Acadia Pharmaceuticals To Present ACP-711 And ACP-204 Updates, NUPLAZID Analysis At 2025 International Parkinson's Congress October 5-9, 2025

Author: Benzinga Newsdesk | October 02, 2025 08:06am

Acadia Pharmaceuticals Inc. (NASDAQ:ACAD) today announced one late-breaker oral platform presentation and two poster presentations to be presented at the International Congress of Parkinson's Disease and Movement Disorders® being held October 5-9, 2025, in Honolulu, Hawaii.

The presentations highlight updates from the company's robust pipeline including preclinical efficacy, safety and mechanism of action findings on Acadia's investigational drug ACP-711, under development for essential tremor, as well as a report on the study design of the Phase 2 ACP-204 study in adults with Lewy body dementia psychosis. The company will also present encore findings from a post-hoc analysis of clinical trial data evaluating duration of illness and response to NUPLAZID® (pimavanserin) in Parkinson's disease psychosis.

Late-Breaker Oral Platform Presentation:

  • Session OPP9/Abstract LBA9/Room 315: Mechanism of Action, Preclinical Efficacy, and Safety Evaluation of SAN711/ACP-711, a Novel GABAA Subunit α3 Selective Modulator, Wednesday, October 8 at 12:00-1:00 p.m. HST

Poster Presentations:

  • E-Poster 1229: Design of the Phase 2, Double-Blind, Placebo-Controlled, Multicenter Study Investigating the Efficacy and Safety of ACP-204, a Novel 5-HT2A Inverse Agonist/Antagonist, in Adults with Lewy Body Dementia Psychosis Tuesday, October 7 at 12:18 p.m. HST
  • E-Poster 1225: Duration of Illness and Response to Pimavanserin in Parkinson's Disease Psychosis: Post-Hoc Analysis of Clinical Trial Data, Tuesday, October 7 at 12:06 p.m. HST

About NUPLAZID® (pimavanserin)

Pimavanserin is a selective serotonin inverse agonist and antagonist preferentially targeting 5-HT2A receptors. These receptors are thought to play an important role in neuropsychiatric disorders. In vitro, pimavanserin demonstrated no appreciable binding affinity for dopamine (including D2), histamine, muscarinic, or adrenergic receptors. Pimavanserin was approved for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis by the U.S. Food and Drug Administration in April 2016 under the trade name NUPLAZID.

Posted In: ACAD

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