Ideaya Biosciences Reports Median Overall Survival Results From Phase 1/2 Trial (OptimUM-01) Of Darovasertib In Combination With Pfizer's Crizotinib1X For Metastatic Uveal Melanoma
Author: Benzinga Newsdesk | October 20, 2025 05:12am
Combination demonstrated median overall survival (OS) of 21.1 months, compared to reported historical mOS of approximately 12 months in published meta-analysis of metastatic uveal melanoma in the first-line setting
Median progression free survival (PFS) of 7.0 months
Confirmed overall response rate (ORR) by RECIST 1.1 of 34%, median duration of response (mDOR) of 9 months and disease control rate (DCR) of 90%