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United Therapeutics Announced The First Clinical Xenotransplantation In Its EXPAND Study Of The UKidney In Patients With End-stage Renal Disease

Author: Benzinga Newsdesk | November 03, 2025 07:07am

United Therapeutics' UKidney is an investigational xenokidney from a pig with 10 gene edits. Six human genes are added to the pig genome to facilitate immunological acceptance and compatibility of the organ in the human recipient. Four porcine genes are inactivated or "knocked out" to reduce the risk of organ rejection and to moderate organ growth.

Posted In: UTHR


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