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Artelo Biosciences, Inc. (NASDAQ:ARTL), a clinical-stage pharmaceutical company focused on modulating lipid-signaling pathways to develop treatments for people living with cancer, pain, dermatological, or neurological conditions, announces the publication of a peer-reviewed article, "The Emerging Role of Fatty Acid Binding Protein 3 (FABP3) in Cancers", in Drug Discovery Today. The publication's lead author is Dr. George Warren, Principal Scientist at Artelo. This publication marks the third in a trilogy of reviews exploring the protumoral roles of FABP isoforms 3, 5, and 7 in cancer biology.
This publication underscores growing evidence that FABP3, similar to FABP5 and FABP7, plays a significant role in cancer progression across multiple tumor types. FABP3 promotes tumorigenic processes through mechanisms linked to lipid metabolism, hypoxia, and ferroptosis—pathways increasingly recognized as critical to cancer cell survival and proliferation. Importantly, both genetic and pharmacological inhibition of FABP3 demonstrated therapeutic benefits in preclinical cancer models.
With this growing body of evidence, Artelo continues to expand its leadership in the FABP inhibitor space. The Company maintains a portfolio of selective, dual, and pan inhibitors targeting FABP3, FABP5, and FABP7, positioning itself to explore multiple therapeutic opportunities across oncology and other indications.
Posted In: ARTL
