NuCana Announces China's National Intellectual Property Administration Has Granted A Composition Of Matter Patent For NUC-7738, Its Novel Anti-Cancer Agent

Author: Benzinga Newsdesk | November 05, 2025 08:02am

NuCana plc (NASDAQ:NCNA) ("NuCana" or the "Company") announced that the China National Intellectual Property Administration ("CNIPA") has granted an important patent covering the composition of matter for NUC-7738.   This patent (ZL 202010794701.2) is expected to serve as a key component of the patent protection for NUC-7738, which currently consists of over 85 issued patents worldwide. The composition of matter patent covers the chemical structure of NUC-7738, NuCana's novel anti-cancer agent currently being evaluated in a Phase 1/2 clinical study (NuTide:701) in combination with pembrolizumab for patients with PD-1 inhibitor refractory or resistant melanoma. Securing this patent represents an important milestone for NuCana, strengthening its long-term global intellectual property strategy, while supporting potential opportunities to address unmet needs for innovative cancer therapies in China.

Hugh S. Griffith, NuCana's Founder and Chief Executive Officer said: "We welcome the CNIPA's decision to grant this important new patent, which further strengthens the intellectual property protection of NUC-7738. The encouraging clinical data observed to date, together with the recent translational findings presented at ESMO 2025, continue to build confidence in the therapeutic potential of NUC-7738 in combination with PD-1 inhibition. As we aim to expand the NuTide:701 study with additional patients, we look forward to reinforcing the overall data package and progressing toward our goal of bringing meaningful new treatment options to patients with cancer."

Posted In: NCNA