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News

Roche's Fenebrutinib Delivers Dual Advances Across RMS And PPMS Showing Significant Relapse Reduction And Disability Slowdown Versus Standard Therapies

Author: Benzinga Newsdesk | November 10, 2025 01:36am

- The first (FENhance 2) of two pivotal RMS studies met its primary endpoint, showing investigational fenebrutinib significantly reduced relapses compared to teriflunomide -

- In a pivotal PPMS study (FENtrepid), fenebrutinib slowed disability progression at least as effectively as Ocrevus, the only approved therapy in PPMS -

- Full data from both studies will be shared at upcoming medical meetings; once the second RMS study (FENhance 1) has read out, which is expected in the first half of 2026, all data together will be considered for submission to regulatory authorities -

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