Protara Therapeutics Announces It Achieves Clinical Success With One Or Two Doses Of TARA-002 In Phase 2 STARBORN-1 Study In 88% Of Participants' No Serious Adverse Events Seen

Author: Benzinga Newsdesk | November 19, 2025 08:06am

Protara Therapeutics, Inc. (Nasdaq: TARA), a clinical-stage company developing transformative therapies for the treatment of cancer and rare diseases, today announced positive interim results from its ongoing Phase 2 open-label STARBORN-1 trial assessing intracystic injection of TARA-002, the Company's investigational cell-based therapy, in pediatric patients with macrocystic and mixed cystic lymphatic malformations (LMs).

The interim analysis includes a total of 12 patients who enrolled in the trial and received ≥ 1 dose of TARA-002 as of the November 12, 2025 data cutoff. Of those, eight patients were evaluable at an eight-week post-treatment assessment, two withdrew prior to the eight-week assessment and two remain in dosing. Patients receive up to four injections of TARA-002 spaced approximately six weeks apart. Of the eight patients who were evaluable, the majority (7/8) achieved clinical success with one or two doses. Only one patient, who presented with a 1,739 ml macrocystic LM, required all four doses, and achieved a complete response.

Posted In: TARA