Biogen To Share New Alzheimer's Drug Data Aiming To Improve Treatment And Patient Convenience

Author: Anusuya Lahiri | November 20, 2025 07:33am

 Biogen Inc. (NASDAQ:BIIB) today announced upcoming scientific presentations at the 18th Clinical Trials on Alzheimer's Disease (CTAD) Conference, taking place December 1-4 in San Diego. Data on LEQEMBI® (lecanemab-irmb) will include findings on subcutaneous administration for initiation dosing, the benefits of continued therapy and estimated time savings over 10 years of treatment based on Phase 3 clinical data, and real-world experience from a post-marketing observational study in Japan and the ALZ-NET registry. The company will also share new insights into BIIB080, an investigational antisense oligonucleotide (ASO) therapy, from a healthy-volunteer biodistribution study, as well as research that helps inform understanding of disease progression.

"Following the introduction of LEQEMBI IQLIK™ in the U.S. for maintenance therapy, we look forward to sharing data that explore its potential for initiation dosing and how it may expand treatment options for patients and care partners across both phases of the treatment journey," said Priya Singhal, M.D., M.P.H., Head of Development at Biogen. "The breadth of data at CTAD also underscores the growing evidence supporting the long-term benefits of continued treatment with LEQEMBI and reflects our ongoing commitment to advancing scientific understanding of Alzheimer's disease."

Key Scientific Sessions and Presentations

Late-Breaking Symposium:

• "Lecanemab Subcutaneous Formulation for Treatment Initiation in Early Alzheimer's Disease: Optimizing Patient Care with a Potential New Option," on Wednesday, December 3 from 3:10-3:50 p.m. PT
  
  
   

Oral Presentations:

• "The Effects of Lecanemab Treatment on Soluble CSF Aβ Protofibrils in Clarity AD," on Tuesday, December 2 from 1:40-1:55 p.m. PT
• "Benefit Continues to Accumulate When Treatment is Continued Beyond Plaque Clearance Estimating Accumulated or Maintained Treatment Benefit in the CLARITY AD and TRAILBLAZER-ALZ2 Trials," on Tuesday, December 2 from 5:05--5:20 p.m. PT
• "Estimating the 10-Year Time-Savings Benefits of Lecanemab Treatment," on Wednesday, December 3 from 2:40-2:55 p.m. PT
• "Interim Analysis of Post-Marketing Observational Study of Lecanemab in Japan," on Thursday, December 4 from 11:40-11:55 a.m. PT

Poster Presentations:

• "Baseline Characteristics and Preliminary Safety from a Multicenter, Safety Surveillance Study of Lecanemab Treatment for Alzheimer's Disease in Real-World Clinical Practice" on Tuesday, December 2 from 7:15 a.m.-5:30 p.m. PT
• "Real-World Clinical Safety and Patient-Reported Outcomes of Treatment with Lecanemab in a New England Alzheimer's Disease Center" on Tuesday, December 2 from 7:15 a.m.-5:30 p.m. PT
• "Stability and Improvement in Early Alzheimer's Disease with Lecanemab: Sub-analysis from a United States Multicenter, Retrospective, Real-World Study" on Tuesday, December 2 from 7:15 a.m.-5:30 p.m. PT
• "Biodistribution of Radiolabeled MAPT Antisense Oligonucleotide BIIB080 Following Intrathecal Administration in Healthy Adults," on Wednesday, December 3 from 7:15 a.m.-5:30 p.m. PT
• "Baseline Study-Partner Reported but not Participant Self-Reported ECog-12 score is Associated with Subsequent Cognitive Progression on CDR-SB over 78 Weeks of Follow-up," on Thursday, December 4 from 7:15 a.m. -5:00 p.m. PT
   

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